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BCL2L1 antibody (pSer62)

BCL2L1 Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6255430
  • Target See all BCL2L1 Antibodies
    BCL2L1 (BCL2-Like 1 (BCL2L1))
    Binding Specificity
    • 28
    • 19
    • 16
    • 14
    • 13
    • 11
    • 10
    • 8
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer62
    Reactivity
    • 203
    • 126
    • 110
    • 48
    • 25
    • 12
    • 10
    • 8
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 152
    • 68
    • 2
    Rabbit
    Clonality
    • 143
    • 79
    Polyclonal
    Conjugate
    • 118
    • 21
    • 11
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This BCL2L1 antibody is un-conjugated
    Application
    • 155
    • 64
    • 59
    • 56
    • 50
    • 29
    • 28
    • 28
    • 26
    • 21
    • 14
    • 9
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    Phospho-BCL-XL (Ser62) Antibody detects endogenous levels of BCL-XL only when phosphorylated at Serine 62.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Purification
    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
    Immunogen
    A synthesized peptide derived from human BCL-XL around the phosphorylation site of Ser62.
    Isotype
    IgG
    Top Product
    Discover our top product BCL2L1 Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    BCL2L1 (BCL2-Like 1 (BCL2L1))
    Alternative Name
    BCL2L1 (BCL2L1 Products)
    Synonyms
    BCL-XL/S antibody, BCL2L antibody, BCLX antibody, BCLXL antibody, BCLXS antibody, Bcl-X antibody, PPP1R52 antibody, bcl-xL antibody, bcl-xS antibody, Bcl(X)L antibody, Bcl-XL antibody, Bcl-Xs antibody, Bcl2l antibody, BclX antibody, bcl-x antibody, Bcl-xl antibody, Bclx antibody, bcl-X antibody, Bcl-xL antibody, BCL-XL antibody, BCL2L1 antibody, bcl-XL antibody, bcl-x(l) antibody, bcl-xl/s antibody, bcl-xs antibody, bcl2l antibody, bclx antibody, bclxl antibody, xR11 antibody, bcl-xl antibody, blp1 antibody, cb1021 antibody, zfBLP1 antibody, BCL2 like 1 antibody, BCL2-like 1 antibody, Bcl2-like 1 antibody, BCL2-like 1 L homeolog antibody, bcl2-like 1 antibody, BCL2L1 antibody, Bcl2l1 antibody, bcl2l1 antibody, bcl2l1.L antibody
    Background

    Description: Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.

    Gene: BCL2L1

    Molecular Weight
    30kDa
    Gene ID
    598
    UniProt
    Q07817
    Pathways
    Apoptosis, Negative Regulation of intrinsic apoptotic Signaling
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