MITF antibody (pSer73, pSer180)
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- Target See all MITF Antibodies
- MITF (Microphthalmia-Associated Transcription Factor (MITF))
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Binding Specificity
- pSer73, pSer180
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Reactivity
- Human, Mouse, Rat, Monkey
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MITF antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC)
- Specificity
- Phospho-MITF (Ser180/73) Antibody detects endogenous levels of MITF only when phosphorylated at Serine 180/73
- Cross-Reactivity
- Human, Monkey, Mouse (Murine), Rat (Rattus)
- Purification
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
- Immunogen
- A synthesized peptide derived from human MITF around the phosphorylation site of Serine 180/73
- Isotype
- IgG
- Top Product
- Discover our top product MITF Primary Antibody
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anti-Microphthalmia-Associated Transcription Factor (MITF) (AA 351-450) antibody
MITF Reactivity: Mouse WB, ELISA, IHC (p), IF (p) Host: Rabbit Polyclonal unconjugated
anti-Microphthalmia-Associated Transcription Factor (MITF) (AA 1-28), (N-Term) antibodyMITF Reactivity: Human WB, IF, FACS Host: Rabbit Polyclonal RB18810 unconjugated
anti-Microphthalmia-Associated Transcription Factor (MITF) antibodyMITF Reactivity: Human WB, IHC, IF Host: Rabbit Monoclonal unconjugated
anti-Microphthalmia-Associated Transcription Factor (MITF) (Ser180), (Ser73) antibodyMITF Reactivity: Human WB, IHC, IF, ELISA Host: Rabbit Polyclonal unconjugated
anti-Microphthalmia-Associated Transcription Factor (MITF) (AA 1-114) antibodyMITF Reactivity: Human FACS, ELISA Host: Mouse Monoclonal 3A2E2 unconjugated
anti-Microphthalmia-Associated Transcription Factor (MITF) antibodyMITF Reactivity: Human, Dog IHC, IF, FACS, StM Host: Rabbit Monoclonal MITF-2987R unconjugated Recombinant Antibody
anti-Microphthalmia-Associated Transcription Factor (MITF) (AA 1-280) antibodyMITF Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Microphthalmia-Associated Transcription Factor (MITF) (Ser180), (Ser73) antibodyMITF Reactivity: Human, Mouse WB, IHC, ELISA, IF/ICC Host: Rabbit Polyclonal unconjugated
anti-Microphthalmia-Associated Transcription Factor (MITF) (AA 1-520) antibodyMITF Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Microphthalmia-Associated Transcription Factor (MITF) antibodyMITF Reactivity: Human, Dog IHC, StM Host: Mouse Monoclonal MITF-915 unconjugated
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- Application Notes
- WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C.Stable for 12 months from date of receipt
- Expiry Date
- 12 months
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- Target
- MITF (Microphthalmia-Associated Transcription Factor (MITF))
- Alternative Name
- MITF (MITF Products)
- Background
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Description: Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to M-boxes (5'-TCATGTG-3') and symmetrical DNA sequences (E-boxes) (5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.
Gene: MITF
- Molecular Weight
- 52kDa
- Gene ID
- 4286
- UniProt
- O75030
- Pathways
- Chromatin Binding
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