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FTO antibody (N-Term)

FTO Reactivity: Human WB, IF Host: Mouse Monoclonal 5-2H10 unconjugated
Catalog No. ABIN6254099
  • Target See all FTO Antibodies
    FTO (Fat Mass and Obesity-Associated (FTO))
    Binding Specificity
    • 17
    • 15
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 64
    • 27
    • 25
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 57
    • 7
    • 1
    • 1
    Mouse
    Clonality
    • 50
    • 16
    Monoclonal
    Conjugate
    • 31
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FTO antibody is un-conjugated
    Application
    • 53
    • 23
    • 18
    • 14
    • 14
    • 11
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Cross-Reactivity
    Human, Mouse (Murine), Rat (Rattus)
    Predicted Reactivity
    bovine, canine, horse, non-human primate, sheep
    Purification
    Protein G purified culture supernatant
    Immunogen
    Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH
    Clone
    5-2H10
    Isotype
    IgG
    Top Product
    Discover our top product FTO Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
    Storage
    -20 °C
  • Mao, Dong, Liu, Guo, Ma, Shen, Qian: "m6A in mRNA coding regions promotes translation via the RNA helicase-containing YTHDC2." in: Nature communications, Vol. 10, Issue 1, pp. 5332, (2020) (PubMed).

    Liu, Zhou, Mao, Ji, Qian: "Programmable RNA N6-methyladenosine editing by CRISPR-Cas9 conjugates." in: Nature chemical biology, Vol. 15, Issue 9, pp. 865-871, (2019) (PubMed).

    Zhou, Wan, Shu, Mao, Liu, Yuan, Zhang, Hess, Brüning, Qian: "N6-Methyladenosine Guides mRNA Alternative Translation during Integrated Stress Response." in: Molecular cell, Vol. 69, Issue 4, pp. 636-647.e7, (2019) (PubMed).

    Wang, Li, Yue, Wang, Kumar, Wechsler-Reya, Zhang, Ogawa, Kellis, Duester, Zhao: "N6-methyladenosine RNA modification regulates embryonic neural stem cell self-renewal through histone modifications." in: Nature neuroscience, Vol. 21, Issue 2, pp. 195-206, (2019) (PubMed).

    Yu, Chen, Huang, Zhu, Song, Zhu, Park, Ji: "Dynamic m6A modification regulates local translation of mRNA in axons." in: Nucleic acids research, Vol. 46, Issue 3, pp. 1412-1423, (2019) (PubMed).

    Zhou, Wan, Gao, Zhang, Jaffrey, Qian: "Dynamic m(6)A mRNA methylation directs translational control of heat shock response." in: Nature, Vol. 526, Issue 7574, pp. 591-4, (2015) (PubMed).

  • Target
    FTO (Fat Mass and Obesity-Associated (FTO))
    Alternative Name
    FTO (FTO Products)
    Synonyms
    AW743446 antibody, mKIAA1752 antibody, RGD1305121 antibody, FTO, alpha-ketoglutarate dependent dioxygenase antibody, fat mass and obesity associated antibody, fat mass and obesity associated L homeolog antibody, FTO antibody, Fto antibody, fto.L antibody
    Molecular Weight
    '58 kDa
    Gene ID
    79068
    UniProt
    Q9C0B1
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