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MECP2 antibody (pSer421)

Name: MECP2 antibody (pSer421)
Brand: antibodies-online
SKU: ABIN6254071
Price: 594 USD
Availability: InStock

MECP2 Reactivity: Mouse WB Host: Rabbit Polyclonal unconjugated

Western blot of mouse whole brain lysate showing specific immunolabeling of the ~55 kDa truncated MeCP2 protein phosphorylated at Ser421 in the first lane (-). (MECP2 antibody (pSer421))

1 image

(1 reference)

Catalog No. ABIN6254071

Datasheet as PDF

Target See all MECP2 Antibodies

MECP2 (Methyl CpG Binding Protein 2 (MECP2))
Binding Specificity
19

11

9

8

7

7

6

3

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
pSer421
Reactivity
102

39

31

6

6

5

4

4

3

3

3

1

1

1
Mouse
Host
100

7

1
Rabbit
Compatible Secondaries
Clonality
101

7
Polyclonal
Conjugate
62

10

8

8

7

7

1

1

1

1

1

1
This MECP2 antibody is un-conjugated
Application
79

64

36

30

12

10

8

5

5

3

2

1

1
Western Blotting (WB)

Cross-Reactivity

Mouse (Murine), Rat (Rattus)

Predicted Reactivity

human, non-human primate

Purification

Antigen Affinity Purified from Pooled Serum

Immunogen

Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser421 conjugated to KLH

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MECP2 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated

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anti-Methyl CpG Binding Protein 2 (MECP2) antibody
MECP2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated

Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Buffer

100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Storage

-20 °C
Buck, ONeill, Stitzel et al.: "Developmental nicotine exposure engenders intergenerational downregulation and aberrant posttranslational modification of cardinal epigenetic factors in the frontal cortices, striata, and hippocampi ..." in: Epigenetics & chromatin, Vol. 13, Issue 1, pp. 13, (2020) (PubMed).
Target

MECP2 (Methyl CpG Binding Protein 2 (MECP2))

Alternative Name

MECP2 (MECP2 Products)

Synonyms

AUTSX3 antibody, MRX16 antibody, MRX79 antibody, MRXS13 antibody, MRXSL antibody, PPMX antibody, RS antibody, RTS antibody, RTT antibody, 1500041B07Rik antibody, BB130002 antibody, D630021H01Rik antibody, Mbd5 antibody, WBP10 antibody, wu:fk96a04 antibody, zgc:111857 antibody, methyl-CpG binding protein 2 antibody, methyl CpG binding protein 2 antibody, methyl-CpG binding protein 2 S homeolog antibody, MECP2 antibody, Mecp2 antibody, mecp2 antibody, mecp2.S antibody

Molecular Weight

'55 kDa

Gene ID

17257

UniProt

Q9Z2D6

Pathways

Inositol Metabolic Process, Chromatin Binding, Synaptic Membrane