ITGAL antibody

Catalog No. ABIN6253839

Product Details anti-ITGAL Antibody

Target: ITGAL (Integrin alpha-L (ITGAL))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ITGAL antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunocytochemistry (ICC)

Specificity: DF1524 produces IgG2b mouse immunoglobulins specific for CD11a. It can be used for flow cytometry and immunohistochemistry for the detection of CD11a positive leucocytes

Purity: PURE

Clone: DF1524

Isotype: IgG2b

Application Details

Application Notes: immunohistochemistry on cytospots,  Immunohistochemistry on frozen tissue sections

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: 4 °C

Target Details for ITGAL

Target: ITGAL (Integrin alpha-L (ITGAL))

Alternative Name: CD11a (ITGAL Products)

Synonyms: CD11A antibody, LFA-1 antibody, LFA1A antibody, (p180) antibody, Cd11a antibody, LFA-1A antibody, Ly-15 antibody, Ly-21 antibody, CD11a antibody, ITGAL antibody, integrin subunit alpha L antibody, integrin alpha L antibody, ITGAL antibody, Itgal antibody

Background: Antigen distribution: CD11a antigens are expressed on lymphocytes, granulocytes, monocytes and macrophages, with increased levels on memory T cells [1,2]. CD11a (integrinaL subunit) combines with CD18 (integrin b2 subunit) to form the integrin LFA-1 (CD11a/CD18). The three ligands for LFA-1 are CD54 (ICAM-1), CD102 (ICAM-2) and CD50 (ICAM-3), each of which contains IgSF domains. DF1524 was clustered at the Leucocyte Typing Workshop IV [5]. Cellular Expression: Lymphocytes, granulocytes, monocytes and macrophages.

Pathways: Activated T Cell Proliferation, Integrin Complex