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Very Low Density Lipoprotein (VLDL) (C-Term) antibody

VLDL Reactivity: Human, Rat WB, FACS, IHC (p), IF Host: Mouse Monoclonal VLDLR-1337 unconjugated
Catalog No. ABIN6252626
  • Target See all Very Low Density Lipoprotein (VLDL) Antibodies
    Very Low Density Lipoprotein (VLDL)
    Binding Specificity
    C-Term
    Reactivity
    Human, Rat
    Host
    • 3
    • 1
    Mouse
    Clonality
    • 4
    Monoclonal
    Conjugate
    • 3
    • 1
    Un-conjugated
    Application
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Purification
    Protein G affinity chromatography
    Immunogen
    A human recombinant partial protein from the C-terminal region was used as the immunogen for this VLDL Receptor antibody.
    Clone
    VLDLR-1337
    Isotype
    IgG1
    Top Product
    Discover our top product VLDL Primary Antibody
  • Application Notes
    Flow Cytometry: 0.5-1 μg/10^6 cells in 0.1ml

    IF: 1-2 μg/mL

    Western blot: 1-2 μg/mL

    IHC (FFPE): 1-2 μg/mL for 30 min at RT

    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the VLDL Receptor antibody to be titered up or down for optimal performance.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.2 mg/mL
    Buffer
    PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot and Store at -20C. Avoid freez-thaw cycles.
  • Target
    Very Low Density Lipoprotein (VLDL)
    Alternative Name
    VLDL (VLDL Products)
    Synonyms
    425O18-1 antibody, 8D6 antibody, D17Ertd716e antibody, NG29 antibody, VLDL antibody, CD320 antigen antibody, Cd320 antibody
    Background
    Very Low Density Lipoprotein Receptor (VLDLR/VLDL receptor) is a member of the LDL receptor gene family which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDL receptor is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.
    Gene ID
    7436
    UniProt
    P98155
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