EPC1 antibody (AA 425-460)

Catalog No. ABIN6244308

Product Details anti-EPC1 Antibody

Target: EPC1 (Enhancer of Polycomb Homolog 1 (EPC1))

Binding Specificity: AA 425-460

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPC1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Epc1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 425-460 amino acids from the Central region of Mouse Epc1.

Clone: RB51001

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for EPC1

Target: EPC1 (Enhancer of Polycomb Homolog 1 (EPC1))

Alternative Name: Epc1 (EPC1 Products)

Synonyms: EPC1 antibody, Epl1 antibody, 2400007E14Rik antibody, 5730566F07Rik antibody, A930032N02Rik antibody, epc1 antibody, enhancer of polycomb homolog 1 antibody, enhancer of polycomb homolog 1 (Drosophila) a antibody, enhancer of polycomb homolog 1 (Drosophila) antibody, enhancer of polycomb homolog 1 L homeolog antibody, EPC1 antibody, epc1a antibody, Epc1 antibody, epc1 antibody, epc1.L antibody

Background: Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage (By similarity).

Molecular Weight: 90411

UniProt: Q8C9X6

Pathways: Regulation of Muscle Cell Differentiation