Mare/Nprl3/C16orf35 antibody (AA 86-117)

Catalog No. ABIN6244303

Product Details anti-Mare/Nprl3/C16orf35 Antibody

Target: Mare/Nprl3/C16orf35 (C16orf35) (MARE (C16orf35))

Binding Specificity: AA 86-117

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Mare/Nprl3/C16orf35 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NPRL3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 86-117 amino acids from human NPRL3.

Clone: RB54296

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for Mare/Nprl3/C16orf35

Target: Mare/Nprl3/C16orf35 (C16orf35) (MARE (C16orf35))

Alternative Name: NPRL3 (C16orf35 Products)

Synonyms: C16orf35 antibody, CGTHBA antibody, HS-40 antibody, MARE antibody, NPR3 antibody, RMD11 antibody, Aag antibody, HS-26 antibody, Mare antibody, Phg antibody, Prox1 antibody, m(alpha)RE antibody, RGD1308665 antibody, c16orf35 antibody, cgthba antibody, hs-40 antibody, mare antibody, npr3 antibody, nprl3 antibody, rmd11 antibody, NPR3 like, GATOR1 complex subunit antibody, nitrogen permease regulator-like 3 antibody, NPR3-like, GATOR1 complex subunit antibody, NPR3-like, GATOR1 complex subunit L homeolog antibody, NPRL3 antibody, Nprl3 antibody, nprl3.L antibody

Background: As a component of the GATOR1 complex, inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC- containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling.

Molecular Weight: 63605

UniProt: Q12980