TXNRD1 antibody (AA 516-550)

Catalog No. ABIN6244289

Product Details anti-TXNRD1 Antibody

Target: TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))

Binding Specificity: AA 516-550

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TXNRD1 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: Pig, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TXNRD1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 516-550 amino acids from human TXNRD1.

Clone: RB56183

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for TXNRD1

Target: TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))

Alternative Name: TXNRD1 (TXNRD1 Products)

Synonyms: TrxR1 antibody, cb682 antibody, fb83a08 antibody, wu:fb83a08 antibody, GB14972 antibody, MGC85342 antibody, NADPH-dependent thioredoxin reductase C antibody, T32G6.20 antibody, T32G6_20 antibody, GRIM-12 antibody, TR antibody, TR1 antibody, TRXR1 antibody, TXNR antibody, Tr antibody, thioredoxin reductase 1 antibody, thioredoxin reductase 1 L homeolog antibody, NADPH-dependent thioredoxin reductase C antibody, ThioRedoXin Reductase antibody, TXNRD1 antibody, txnrd1 antibody, Trxr-1 antibody, txnrd1.L antibody, NTRC antibody, trxr-1 antibody, Txnrd1 antibody

Background: Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.

Molecular Weight: 70906

UniProt: Q16881

Pathways: Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis