TSG101 antibody
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- Target See all TSG101 Antibodies
- TSG101 (Tumor Susceptibility Gene 101 (TSG101))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This TSG101 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- This antibody is purified through a protein G column, followed by dialysis against PBS.
- Immunogen
- This antibody is generated from a mouse immunized with a recombinant protein from human.
- Clone
- 1883CT788-47-15-46
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product TSG101 Primary Antibody
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- Application Notes
- WB: 1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Expiry Date
- 6 months
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- Target
- TSG101 (Tumor Susceptibility Gene 101 (TSG101))
- Alternative Name
- TSG101 (TSG101 Products)
- Background
- Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis, the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses.
- Molecular Weight
- 43944
- UniProt
- Q99816
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