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TIGIT antibody (AA 12-142)
TIGIT
Reactivity: Human, Mouse
WB
Host: Rabbit
Polyclonal
RB55818
unconjugated
Product Details anti-TIGIT Antibody
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Target
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TIGIT
(T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT))
Binding Specificity
All epitopes for TIGIT antibodies
AA 12-142
Reactivity
All reactivities for TIGIT antibodies
Human, Mouse
Host
All hosts for TIGIT antibodies
Rabbit
Clonality
All clonalities for TIGIT antibodies
Polyclonal
Conjugate
All conjugates for TIGIT antibodies
This TIGIT antibody is un-conjugated
Application
All applications for TIGIT antibodies
Western Blotting (WB)
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This TIGIT antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 12-142 amino acids from human TIGIT.
Clone
RB55818
Isotype
Ig Fraction
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Discover our top product TIGIT Primary Antibody
Alternatives
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Application Details
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Application Notes
WB: 1:2000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Expiry Date
6 months
Target Details for TIGIT
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Target
TIGIT
(T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT))
Alternative Name
TIGIT (TIGIT Products )
Synonyms
VSIG9 antibody, VSTM3 antibody, WUCAM antibody, ENSMUSG00000071552 antibody, Vstm3 antibody, RGD1563191 antibody, T-cell immunoreceptor with Ig and ITIM domains antibody, T cell immunoreceptor with Ig and ITIM domains antibody, TIGIT antibody, Tigit antibody
Background
Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.
Molecular Weight
26319
UniProt
Q495A1
Pathways
Cancer Immune Checkpoints
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