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SH3PXD2B antibody (AA 596-628)

SH3PXD2B Reactivity: Human WB, FACS Host: Rabbit Polyclonal RB55314 unconjugated
Catalog No. ABIN6244202
  • Target See all SH3PXD2B Antibodies
    SH3PXD2B (SH3 and PX Domains 2B (SH3PXD2B))
    Binding Specificity
    • 1
    • 1
    • 1
    AA 596-628
    Reactivity
    Human
    Host
    • 3
    Rabbit
    Clonality
    • 3
    Polyclonal
    Conjugate
    • 3
    This SH3PXD2B antibody is un-conjugated
    Application
    Western Blotting (WB), Flow Cytometry (FACS)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This SH3PXD2B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 596-628 amino acids from human SH3PXD2B.
    Clone
    RB55314
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:2000. FC: 1:25
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Target
    SH3PXD2B (SH3 and PX Domains 2B (SH3PXD2B))
    Alternative Name
    SH3PXD2B (SH3PXD2B Products)
    Synonyms
    FAD49 antibody, FTHS antibody, HOFI antibody, KIAA1295 antibody, TKS4 antibody, TSK4 antibody, G431001E03Rik antibody, fad49 antibody, SH3 and PX domains 2B antibody, SH3PXD2B antibody, Sh3pxd2b antibody
    Background
    Adapter protein involved in invadopodia and podosome formation and extracellular matrix degradation. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. Plays a role in mitotic clonal expansion during the immediate early stage of adipocyte differentiation (By similarity).
    Molecular Weight
    101579
    UniProt
    A1X283
    Pathways
    Positive Regulation of fat Cell Differentiation
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