SMG7 antibody (C-Term)

Catalog No. ABIN6244188

Product Details anti-SMG7 Antibody

Target: SMG7 (Smg-7 Homolog, Nonsense Mediated mRNA Decay Factor (SMG7))

Binding Specificity: AA 896-930, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMG7 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SMG7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 896-930 amino acids from the C-terminal region of human SMG7.

Clone: RB49260

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for SMG7

Target: SMG7 (Smg-7 Homolog, Nonsense Mediated mRNA Decay Factor (SMG7))

Alternative Name: SMG7 (SMG7 Products)

Synonyms: 9430023P16Rik antibody, mKIAA0250 antibody, C1orf16 antibody, EST1C antibody, SGA56M antibody, Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) antibody, SMG7, nonsense mediated mRNA decay factor antibody, Smg7 antibody, SMG7 antibody

Background: Plays a role in nonsense-mediated mRNA decay. Recruits UPF1 to cytoplasmic mRNA decay bodies. Together with SMG5 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation.

Molecular Weight: 127282

UniProt: Q92540