MIB2 antibody (AA 216-249)

Catalog No. ABIN6244186

Product Details anti-MIB2 Antibody

Target: MIB2 (E3 ubiquitin-protein ligase MIB2 (MIB2))

Binding Specificity: AA 216-249

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MIB2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MIB2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 216-249 amino acids from human MIB2.

Clone: RB54754

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for MIB2

Target: MIB2 (E3 ubiquitin-protein ligase MIB2 (MIB2))

Alternative Name: MIB2 (MIB2 Products)

Synonyms: ZZANK1 antibody, ZZZ5 antibody, 2210008I11Rik antibody, Zzank1 antibody, skd antibody, mib2 antibody, mindbomb E3 ubiquitin protein ligase 2 antibody, mindbomb E3 ubiquitin protein ligase 2 S homeolog antibody, MIB2 antibody, Mib2 antibody, mib2 antibody, mib2.S antibody

Background: E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors (By similarity).

Molecular Weight: 109939

UniProt: Q96AX9

Pathways: Notch Signaling