UHRF2 antibody (AA 472-505)

Catalog No. ABIN6244180

Product Details anti-UHRF2 Antibody

Target: UHRF2 (Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase (UHRF2))

Binding Specificity: AA 472-505

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UHRF2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Uhrf2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 472-505 amino acids from the Central region of Mouse Uhrf2.

Clone: RB52404

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for UHRF2

Target: UHRF2 (Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase (UHRF2))

Alternative Name: Uhrf2 (UHRF2 Products)

Synonyms: NIRF antibody, RNF107 antibody, URF2 antibody, 2310065A22Rik antibody, AI426270 antibody, AW214556 antibody, D130071B19Rik antibody, Nirf antibody, ubiquitin like with PHD and ring finger domains 2 antibody, ubiquitin-like, containing PHD and RING finger domains 2 antibody, ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase L homeolog antibody, UHRF2 antibody, Uhrf2 antibody, uhrf2.L antibody

Background: E3 SUMO-, but not ubiquitin-, protein ligase for ZNF131 (By similarity). E3 ubiquitin-protein ligase that is an intermolecular hub protein in the cell cycle network. Ubiquitinates cyclins, CCND1 and CCNE1, in an apparently phosphorylation-independent manner and induces G1 arrest. Also ubiquitinates PCNP leading to its degradation by the proteasome. Through cooperative DNA and histone binding, may contribute to a tighter epigenetic control of gene expression in differentiated cells.

Molecular Weight: 90106

UniProt: Q7TMI3