This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This CAPN2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 301-335 amino acids from the Central region of human CAPN2.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Expiry Date
6 months
Zhao, Cui, Zhou, Li, Zhang, Sun, Han, Zou, Wang, Li, Wang: "Calpain-Calcineurin-Nuclear Factor Signaling and the Development of Atrial Fibrillation in Patients with Valvular Heart Disease and Diabetes." in: Journal of diabetes research, Vol. 2016, pp. 4639654, (2016) (PubMed).
Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226' (PubMed:< a href="http://www.uniprot.org/citations/17650508" target="_blank">17650508).