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ATG10 antibody (N-Term)

ATG10 Reactivity: Human IHC (p) Host: Rabbit Polyclonal RB7550 unconjugated
Catalog No. ABIN6244154
  • Target See all ATG10 Antibodies
    ATG10 (Autophagy Related 10 (ATG10))
    Binding Specificity
    • 15
    • 13
    • 8
    • 8
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    AA 15-45, N-Term
    Reactivity
    • 70
    • 14
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 68
    • 1
    • 1
    Rabbit
    Clonality
    • 68
    • 2
    Polyclonal
    Conjugate
    • 26
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATG10 antibody is un-conjugated
    Application
    • 35
    • 27
    • 25
    • 13
    • 13
    • 9
    • 8
    • 7
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This ATG10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15~45 amino acids from the N-term of human APG10L.
    Clone
    RB7550
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ATG10 Primary Antibody
  • Application Notes
    IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Sanchez, Penfornis, Oskowitz, Boonjindasup, Cai, Dhule, Rowan, Kelekar, Krause, Pochampally: "Activation of autophagy in mesenchymal stem cells provides tumor stromal support." in: Carcinogenesis, Vol. 32, Issue 7, pp. 964-72, (2011) (PubMed).

  • Target
    ATG10 (Autophagy Related 10 (ATG10))
    Alternative Name
    ATG10 (ATG10 Products)
    Synonyms
    APG10 antibody, APG10L antibody, pp12616 antibody, Atg10 antibody, ATG10 antibody, MGC123341 antibody, im:7153729 antibody, zgc:123341 antibody, ATATG10 antibody, autophagy 10 antibody, DDBDRAFT_0190076 antibody, DDBDRAFT_0252608 antibody, DDB_0190076 antibody, DDB_0252608 antibody, 5330424L23Rik antibody, 5430428K15Rik antibody, AI852123 antibody, Agp10 antibody, Apg10l antibody, Apg10p antibody, Atg10l antibody, autophagy related 10 antibody, autophagy-related 10 antibody, AuTophaGy (yeast Atg homolog) antibody, ATG10 autophagy related 10 homolog (S. cerevisiae) antibody, autophagocytosis-associated family protein antibody, E2-like conjugating enzyme antibody, hypothetical protein antibody, autophagy protein 10 antibody, autophagy-related protein 10 antibody, ATG10 antibody, Atg10 antibody, atg-10 antibody, atg10 antibody, CAALFM_C302930WA antibody, APG10 antibody
    Background
    Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG10 is an ATG12-conjugating enzyme (E2-like enzyme) that likely serves as an ATG5-recognition molecule. This protein interacts with MAP1LC3A. By interacting with MAP1LC3A, it plays a role in the conjugation of ATG12 to ATG5. APG10 also is able to directly interact either with ATG5 or ATG7.
    Molecular Weight
    25279
    NCBI Accession
    NP_001124500, NP_113670
    UniProt
    Q9H0Y0
    Pathways
    ER-Nucleus Signaling, Autophagy
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