PHC1 antibody (AA 308-342)

Catalog No. ABIN6244140

Product Details anti-PHC1 Antibody

Target: PHC1 (Polyhomeotic-Like 1 (PHC1))

Binding Specificity: AA 308-342

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHC1 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PHC1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 308-342 amino acids from human PHC1.

Clone: RB54227

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for PHC1

Target: PHC1 (Polyhomeotic-Like 1 (PHC1))

Alternative Name: PHC1 (PHC1 Products)

Synonyms: EDR1 antibody, HPH1 antibody, RAE28 antibody, AW557034 antibody, Edr antibody, Edr1 antibody, Mph1 antibody, Rae-28 antibody, rae28 antibody, polyhomeotic homolog 1 antibody, polyhomeotic-like 1 (Drosophila) antibody, Phc1 antibody, PHC1 antibody

Background: Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Required for proper control of cellular levels of GMNN expression.

Molecular Weight: 105534

UniProt: P78364