This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This VAC14 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 769-802 amino acids from the C-terminal region of human VAC14.
The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Acts as a positive activator of PIKfyve kinase activity. Also required to maintain normal levels of phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 5-phosphate (PtdIns(5)P). Plays a role in the biogenesis of endosome carrier vesicles (ECV) / multivesicular bodies (MVB) transport intermediates from early endosomes.