YARS2 antibody (N-Term)

Catalog No. ABIN6244048

Product Details anti-YARS2 Antibody

Target: YARS2 (Tyrosyl-tRNA Synthetase 2, Mitochondrial (YARS2))

Binding Specificity: AA 43-71, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YARS2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This YARS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 43-71 amino acids from the N-terminal region of human YARS2.

Clone: RB14933

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-YARS2 antibody (ABIN6244048)

Riley, Menezes, Rudinger-Thirion, Duff, de Lonlay, Rotig, Tchan, Davis, Cooper, Christodoulou: "Phenotypic variability and identification of novel YARS2 mutations in YARS2 mitochondrial myopathy, lactic acidosis and sideroblastic anaemia." in: Orphanet journal of rare diseases, Vol. 8, pp. 193, (2014) (PubMed).

Target Details for YARS2

Target: YARS2 (Tyrosyl-tRNA Synthetase 2, Mitochondrial (YARS2))

Alternative Name: YARS2 (YARS2 Products)

Synonyms: 2210023C10Rik antibody, tyrRS antibody, CGI-04 antibody, RGD1311696 antibody, MLASA2 antibody, MT-TYRRS antibody, TYRRS antibody, tyrosyl-tRNA synthetase 2 (mitochondrial) antibody, tyrosyl-tRNA synthetase 2 antibody, Yars2 antibody, YARS2 antibody

Background: YARS2 catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr)

Molecular Weight: 53199

NCBI Accession: NP_001035526

UniProt: Q9Y2Z4