SOX7 antibody (AA 224-258)

Catalog No. ABIN6244006

Product Details anti-SOX7 Antibody

Target: SOX7 (SRY (Sex Determining Region Y)-Box 7 (SOX7))

Binding Specificity: AA 224-258

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX7 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SOX7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 224-258 amino acids from the Central region of human SOX7.

Clone: RB51583

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for SOX7

Target: SOX7 (SRY (Sex Determining Region Y)-Box 7 (SOX7))

Alternative Name: SOX7 (SOX7 Products)

Synonyms: sox7-A antibody, xSox7 antibody, SRY-box 7 antibody, SRY (sex determining region Y)-box 7 antibody, SRY box 7 antibody, SRY-box 7 L homeolog antibody, SOX7 antibody, Sox7 antibody, sox7 antibody, sox7.L antibody

Background: Binds to and activates the CDH5 promoter, hence plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium and blocks further differentiation into blood precursors (By similarity). May be required for the survival of both hematopoietic and endothelial precursors during specification (By similarity). Competes with GATA4 for binding and activation of the FGF3 promoter (By similarity). Represses Wnt/beta-catenin-stimulated transcription, probably by targeting CTNNB1 to proteasomal degradation. Binds the DNA sequence 5'- AACAAT-3'.

Molecular Weight: 42197

UniProt: Q9BT81

Pathways: Positive Regulation of Endopeptidase Activity