PHC3 antibody (AA 819-850)

Catalog No. ABIN6243947

Product Details anti-PHC3 Antibody

Target: PHC3 (Polyhomeotic Homolog 3 (PHC3))

Binding Specificity: AA 819-850

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHC3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PHC3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 819-850 amino acids from human PHC3.

Clone: RB54120

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000. IHC-P: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for PHC3

Target: PHC3 (Polyhomeotic Homolog 3 (PHC3))

Alternative Name: PHC3 (PHC3 Products)

Synonyms: EDR3 antibody, HPH3 antibody, E030046K01Rik antibody, Edr3 antibody, Hph3 antibody, polyhomeotic homolog 3 antibody, polyhomeotic-like 3 (Drosophila) antibody, Phc3 antibody, PHC3 antibody

Background: Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Molecular Weight: 106162

UniProt: Q8NDX5