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PHC3 antibody (AA 819-850)

PHC3 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB54120 unconjugated
Catalog No. ABIN6243947
  • Target See all PHC3 Antibodies
    PHC3 (Polyhomeotic Homolog 3 (PHC3))
    Binding Specificity
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 819-850
    Reactivity
    • 22
    • 14
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 21
    • 1
    Rabbit
    Clonality
    • 22
    Polyclonal
    Conjugate
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PHC3 antibody is un-conjugated
    Application
    • 11
    • 6
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This PHC3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 819-850 amino acids from human PHC3.
    Clone
    RB54120
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:2000. IHC-P: 1:25
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Target
    PHC3 (Polyhomeotic Homolog 3 (PHC3))
    Alternative Name
    PHC3 (PHC3 Products)
    Synonyms
    EDR3 antibody, HPH3 antibody, E030046K01Rik antibody, Edr3 antibody, Hph3 antibody, polyhomeotic homolog 3 antibody, polyhomeotic-like 3 (Drosophila) antibody, Phc3 antibody, PHC3 antibody
    Background
    Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
    Molecular Weight
    106162
    UniProt
    Q8NDX5
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