NDN antibody (N-Term)

Catalog No. ABIN6243906

Product Details anti-NDN Antibody

Target: NDN (Necdin Homolog (Mouse) (NDN))

Binding Specificity: AA 75-109, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDN antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NDN antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 75-109 amino acids from the N-terminal region of human NDN.

Clone: RB51025

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for NDN

Target: NDN (Necdin Homolog (Mouse) (NDN))

Alternative Name: NDN (NDN Products)

Synonyms: LOC574323 antibody, AI528698 antibody, Peg6 antibody, NDN antibody, HsT16328 antibody, PWCR antibody, necdin, MAGE family member antibody, necdin antibody, NDN antibody, Ndn antibody

Background: Growth suppressor that facilitates the entry of the cell into cell cycle arrest. Functionally similar to the retinoblastoma protein it binds to and represses the activity of cell-cycle- promoting proteins such as SV40 large T antigen, adenovirus E1A, and the transcription factor E2F. Necdin also interacts with p53 and works in an additive manner to inhibit cell growth. Functions also as transcription factor and binds directly to specific guanosine-rich DNA sequences (By similarity).

Molecular Weight: 36086

UniProt: Q99608

Pathways: Neurotrophin Signaling Pathway