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MAGI3 antibody (AA 1330-1360)
MAGI3
Reactivity: Human
WB
Host: Rabbit
Polyclonal
RB53923
unconjugated
Product Details anti-MAGI3 Antibody
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Target
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MAGI3
(Membrane Associated Guanylate Kinase, WW and PDZ Domain Containing 3 (MAGI3))
Binding Specificity
All epitopes for MAGI3 antibodies
AA 1330-1360
Reactivity
All reactivities for MAGI3 antibodies
Human
Host
All hosts for MAGI3 antibodies
Rabbit
Clonality
All clonalities for MAGI3 antibodies
Polyclonal
Conjugate
All conjugates for MAGI3 antibodies
This MAGI3 antibody is un-conjugated
Application
All applications for MAGI3 antibodies
Western Blotting (WB)
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This MAGI3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1330-1360 amino acids from human MAGI3.
Clone
RB53923
Isotype
Ig Fraction
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Alternatives
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Application Details
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Application Notes
WB: 1:2000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Expiry Date
6 months
Target Details for MAGI3
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Target
MAGI3
(Membrane Associated Guanylate Kinase, WW and PDZ Domain Containing 3 (MAGI3))
Alternative Name
MAGI3 (MAGI3 Products )
Synonyms
Slipr antibody, MAGI-3 antibody, RP4-730K3.1 antibody, dJ730K3.2 antibody, 4732496O19Rik antibody, 6530407C02Rik antibody, AA407180 antibody, AI120132 antibody, mKIAA1634 antibody, membrane associated guanylate kinase, WW and PDZ domain containing 3 antibody, Magi3 antibody, MAGI3 antibody
Background
Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes. Cooperates with PTEN to modulate the kinase activity of AKT1. Its interaction with PTPRB and tyrosine phosphorylated proteins suggests that it may link receptor tyrosine phosphatase with its substrates at the plasma membrane. In polarized epithelial cells, involved in efficient trafficking of TGFA to the cell surface. Regulates the ability of LPAR2 to activate ERK and RhoA pathways. Regulates the JNK signaling cascade via its interaction with FZD4 and VANGL2.
Molecular Weight
162949
UniProt
Q5TCQ9
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