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MAD2L2 antibody (C-Term)

MAD2L2 Reactivity: Mouse WB, IF, IHC (p) Host: Rabbit Polyclonal RB48484 unconjugated
Catalog No. ABIN6243877
  • Target See all MAD2L2 Antibodies
    MAD2L2 (MAD2 Mitotic Arrest Deficient-Like 2 (MAD2L2))
    Binding Specificity
    • 15
    • 9
    • 4
    • 1
    • 1
    AA 198-231, C-Term
    Reactivity
    • 41
    • 12
    • 11
    Mouse
    Host
    • 40
    • 2
    Rabbit
    Clonality
    • 32
    • 10
    Polyclonal
    Conjugate
    • 17
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAD2L2 antibody is un-conjugated
    Application
    • 30
    • 14
    • 14
    • 13
    • 7
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This MAD2L2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 198-231 amino acids from the C-terminal region of human MAD2L2.
    Clone
    RB48484
    Isotype
    Ig Fraction
    Top Product
    Discover our top product MAD2L2 Primary Antibody
  • Application Notes
    IF: 1:25. WB: 1:1000. IHC-P: 1:25
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Target
    MAD2L2 (MAD2 Mitotic Arrest Deficient-Like 2 (MAD2L2))
    Alternative Name
    MAD2L2 (MAD2L2 Products)
    Synonyms
    mad2b antibody, 2310033C13Rik antibody, MAD2B antibody, REV7 antibody, mad2B antibody, mad2l2-A antibody, xMAD2L2 antibody, POLZ2 antibody, mad2l2 antibody, zgc:110299 antibody, mitotic arrest deficient 2 like 2 antibody, MAD2 mitotic arrest deficient-like 2 antibody, mitotic arrest deficient 2 like 2 S homeolog antibody, MAD2 mitotic arrest deficient-like 2 (yeast) antibody, si:dkey-23c22.2 antibody, mad2l2 antibody, MAD2L2 antibody, Mad2l2 antibody, mad2l2.S antibody, si:dkey-23c22.2 antibody
    Background
    Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. May also regulate another aspect of cellular response to DNA damage through regulation of the JNK-mediated phosphorylation and activation of the transcriptional activator ELK1. Inhibits the FZR1- and probably CDC20-mediated activation of the anaphase promoting complex APC thereby regulating progression through the cell cycle. Regulates TCF7L2-mediated gene transcription and may play a role in epithelial-mesenchymal transdifferentiation.
    Molecular Weight
    24334
    UniProt
    Q9UI95
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