This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This PPP2R5B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 466-500 amino acids from the C-terminal region of human PPP2R5B.
B56B antibody, PR61B antibody, B'beta antibody, BC026670 antibody, PPP2R5B antibody, ppp2r5e antibody, protein phosphatase 2 regulatory subunit B'beta antibody, protein phosphatase 2, regulatory subunit B', beta antibody, protein phosphatase 2A regulatory subunit B' antibody, protein phosphatase 2 regulatory subunit B', beta antibody, protein phosphatase 2 regulatory subunit Bbeta antibody, PPP2R5B antibody, Ppp2r5b antibody, ppp2r5b antibody, ppp2r5b.L antibody, PPP2R2B antibody
Background
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. The phosphorylated form mediates the interaction between AKT1 and PP2A phosphatase leading to dephosphorylation of AKT1 on the 'Thr-308' and 'Ser-373' residues.