Fbx45 antibody, 2610017J04Rik antibody, AI463119 antibody, BC026799 antibody, zgc:65875 antibody, 3g27 antibody, F-box protein 45 antibody, F-box protein 45 S homeolog antibody, FBXO45 antibody, fbxo45 antibody, Fbxo45 antibody, fbxo45.S antibody
Background
Component of E3 ubiquitin ligase complexes. Required for normal neuromuscular synaptogenesis, axon pathfinding and neuronal migration (By similarity). Plays a role in the regulation of neurotransmission at mature neurons (By similarity). May controls synaptic activity by controlling UNC13A via ubiquitin dependent pathway (By similarity). Specifically recognizes TP73, promoting its ubiquitination and degradation.