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LIN28A antibody (C-Term)

LIN28A Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB14266 unconjugated
Catalog No. ABIN6243718
  • Target See all LIN28A Antibodies
    LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))
    Binding Specificity
    • 15
    • 9
    • 9
    • 7
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 168-198, C-Term
    Reactivity
    • 101
    • 35
    • 27
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 85
    • 18
    Rabbit
    Clonality
    • 80
    • 23
    Polyclonal
    Conjugate
    • 46
    • 8
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LIN28A antibody is un-conjugated
    Application
    • 61
    • 37
    • 24
    • 18
    • 16
    • 14
    • 13
    • 13
    • 9
    • 8
    • 6
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This LIN28A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168~198 amino acids from the C-terminal region of human LIN28A.
    Clone
    RB14266
    Isotype
    Ig Fraction
    Top Product
    Discover our top product LIN28A Primary Antibody
  • Application Notes
    WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Target
    LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))
    Alternative Name
    LIN28A (LIN28A Products)
    Synonyms
    CSDD1 antibody, LIN-28 antibody, LIN28 antibody, ZCCHC1 antibody, lin-28A antibody, AL024421 antibody, ENSMUSG00000070700 antibody, Gm10299 antibody, Lin-28 antibody, Lin28 antibody, Tex17 antibody, csdd1 antibody, lin-28 antibody, lin28 antibody, zcchc1 antibody, sb:cb650 antibody, zgc:55584 antibody, RGD1566408 antibody, lin-28 homolog A antibody, lin-28 homolog A (C. elegans) antibody, lin-28 homolog A S homeolog antibody, LIN28A antibody, Lin28a antibody, lin28a.S antibody, lin28a antibody
    Background
    LIN28A acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. It binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. It is essential for skeletal muscle differentiation through the translational up-regulation of IGF2 expression.
    Molecular Weight
    22743
    NCBI Accession
    NP_078950
    UniProt
    Q9H9Z2
    Pathways
    Stem Cell Maintenance
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