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PERK antibody (AA 530-850)
EIF2AK3
Reactivity: Human, Mouse, Rat
WB
Host: Mouse
Monoclonal
1385CT582-4-39
unconjugated
Product Details anti-PERK Antibody
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Target
See all PERK (EIF2AK3) Antibodies
PERK (EIF2AK3)
(Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3))
Binding Specificity
All epitopes for PERK antibodies
AA 530-850
Reactivity
All reactivities for PERK antibodies
Human, Mouse, Rat
Host
All hosts for PERK antibodies
Mouse
Clonality
All clonalities for PERK antibodies
Monoclonal
Conjugate
All conjugates for PERK antibodies
This PERK antibody is un-conjugated
Application
All applications for PERK antibodies
Western Blotting (WB)
Purification
This antibody is purified through a protein G column, followed by dialysis against PBS.
Immunogen
This EIF2AK3 antibody is generated from a mouse immunized with a recombinant protein conjugated synthetic peptide between 530-850 amino acids from human EIF2AK3.
Clone
1385CT582-4-39
Isotype
IgG1
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Discover our top product EIF2AK3 Primary Antibody
Alternatives
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anti-Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3) (pThr980) antibody
EIF2AK3
Reactivity: Human, Mouse, Rat, Dog, Pig
ELISA, WB, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
WB: 1:250-1:1000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Expiry Date
6 months
Target Details for PERK
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Target
PERK (EIF2AK3)
(Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3))
Alternative Name
EIF2AK3 (EIF2AK3 Products )
Synonyms
EIF2AK3 antibody, AI427929 antibody, Pek antibody, Perk antibody, PEK antibody, PERK antibody, WRS antibody, eukaryotic translation initiation factor 2 alpha kinase 3 antibody, EIF2AK3 antibody, Eif2ak3 antibody
Background
Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin-D1 (CCND1). Involved in control of mitochondrial morphology and function (By similarity).
Molecular Weight
125216
UniProt
Q9NZJ5
Pathways
Hormone Transport , ER-Nucleus Signaling , Positive Regulation of Endopeptidase Activity , Hepatitis C , Unfolded Protein Response
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