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ATG16L1 antibody
ATG16L1
Reactivity: Human
WB, IHC (p)
Host: Mouse
Monoclonal
54CT27-2-6
unconjugated
Product Details anti-ATG16L1 Antibody
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Target
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ATG16L1
(ATG16 Autophagy Related 16-Like 1 (ATG16L1))
Reactivity
All reactivities for ATG16L1 antibodies
Human
Host
All hosts for ATG16L1 antibodies
Mouse
Clonality
All clonalities for ATG16L1 antibodies
Monoclonal
Conjugate
All conjugates for ATG16L1 antibodies
This ATG16L1 antibody is un-conjugated
Application
All applications for ATG16L1 antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is purified through a protein G column, followed by dialysis against PBS.
Immunogen
Purified His-tagged ATG16L1 protein(Fragment) was used to produced this monoclonal antibody.
Clone
54CT27-2-6
Isotype
IgG1 kappa
Top Product
Discover our top product ATG16L1 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB: 1:60. IHC-P: 1:10~50
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Expiry Date
6 months
References for anti-ATG16L1 antibody (ABIN6243484)
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Martinez-Outschoorn, Trimmer, Lin, Whitaker-Menezes, Chiavarina, Zhou, Wang, Pavlides, Martinez-Cantarin, Capozza, Witkiewicz, Flomenberg, Howell, Pestell, Caro, Lisanti, Sotgia : "Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NFκB activation in the tumor stromal microenvironment. " in: Cell cycle (Georgetown, Tex.) , Vol. 9 , Issue 17 , pp. 3515-33 , (2010 ) (PubMed ).
Target Details for ATG16L1
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Target
ATG16L1
(ATG16 Autophagy Related 16-Like 1 (ATG16L1))
Alternative Name
ATG16L1 (ATG16L1 Products )
Background
The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.
Molecular Weight
68265
NCBI Accession
NP_001177195 , NP_001177196 , NP_060444 , NP_110430 , NP_942593
UniProt
Q676U5
Pathways
Autophagy
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