POLR3E antibody (AA 241-271)

Catalog No. ABIN6243424

Product Details anti-POLR3E Antibody

Target: POLR3E (Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E))

Binding Specificity: AA 241-271

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLR3E antibody is un-conjugated

Application: Please inquire

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This RPC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 241~271 amino acids from the central region of human RPC5.

Clone: RB9822

Isotype: Ig Fraction

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-POLR3E antibody (ABIN6243424)

Birch, Tan, Panov, Panova, Andersen, Owen-Hughes, Russell, Lee, Zomerdijk: "FACT facilitates chromatin transcription by RNA polymerases I and III." in: The EMBO journal, Vol. 28, Issue 7, pp. 854-65, (2009) (PubMed).

Target Details for POLR3E

Target: POLR3E (Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E))

Alternative Name: RPC5 (POLR3E Products)

Background: RNA polymerase III synthesizes RNA components of the protein synthesis, pre-mRNA splicing, and tRNA processing apparatuses. The holoenzyme consists of about 15 different subunits. The RPC5 subunit is essential for efficient transcription from both the type 2 VAI and type 3 U6 RNA polymerase III promoters.

Molecular Weight: 79898

NCBI Accession: NP_001244962, NP_001244963, NP_001244964, NP_001244965, NP_060589

UniProt: Q9NVU0