TNRC6A antibody (AA 855-885)

Catalog No. ABIN6243375

Product Details anti-TNRC6A Antibody

Target: TNRC6A (Trinucleotide Repeat Containing 6A (TNRC6A))

Binding Specificity: AA 855-885

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TNRC6A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 855-885 amino acids from the Central region of human TNRC6A.

Clone: RB54170

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for TNRC6A

Target: TNRC6A (Trinucleotide Repeat Containing 6A (TNRC6A))

Alternative Name: TNRC6A

Synonyms: 2010321I05Rik antibody, 3110054G10Rik antibody, AW557223 antibody, CAGH26 antibody, D130023A07Rik antibody, GW182 antibody, Tnrc6 antibody, GW1 antibody, TNRC6 antibody, trinucleotide repeat containing 6a antibody, trinucleotide repeat containing 6A antibody, Tnrc6a antibody, TNRC6A antibody

Background: Plays a role in RNA-mediated gene silencing by both micro-RNAs (miRNAs) and short interfering RNAs (siRNAs). Required for miRNA-dependent repression of translation and for siRNA- dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins. As scaffoldng protein associates with argonaute proteins bound to partially complementary mRNAs and simultaneously can recruit CCR4-NOT and PAN deadenylase complexes.

Molecular Weight: 210297

UniProt: Q8NDV7