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ULK3 antibody (C-Term)

ULK3 Reactivity: Human, Mouse, Rat WB Host: Mouse Monoclonal 1404CT148-89-25 unconjugated
Catalog No. ABIN6243328
  • Target See all ULK3 Antibodies
    ULK3 (Unc-51-Like Kinase 3 (ULK3))
    Binding Specificity
    • 14
    • 10
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 435-468, C-Term
    Reactivity
    • 53
    • 45
    • 15
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 62
    • 5
    • 2
    Mouse
    Clonality
    • 65
    • 4
    Monoclonal
    Conjugate
    • 30
    • 6
    • 6
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ULK3 antibody is un-conjugated
    Application
    • 60
    • 40
    • 10
    • 10
    • 8
    • 6
    • 3
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    Immunogen
    This ULK3 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 435-468 amino acids from the C-terminal region of human ULK3.
    Clone
    1404CT148-89-25
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product ULK3 Primary Antibody
  • Application Notes
    IHC: 1:50. WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Target
    ULK3 (Unc-51-Like Kinase 3 (ULK3))
    Alternative Name
    ULK3 (ULK3 Products)
    Synonyms
    zgc:162196 antibody, 1200015E14Rik antibody, unc-51 like kinase 3 antibody, unc-51 like kinase 3 L homeolog antibody, unc-51-like kinase 3 antibody, ULK3 antibody, ulk3 antibody, Ulk3 antibody, ulk3.L antibody
    Background
    Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy. Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GLI3). Positively regulates SHH signaling in the presence of SHH: dissociates from SUFU, autophosphorylates and mediates phosphorylation of GLI2, activating it and promoting its nuclear translocation. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently. Also acts as a regulator of autophagy: following cellular senescence, able to induce autophagy.
    Molecular Weight
    53444
    UniProt
    Q6PHR2
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