RYK antibody (AA 260-565)

Catalog No. ABIN6243294

Product Details anti-RYK Antibody

Target: RYK (RYK Receptor-Like Tyrosine Kinase (RYK))

Binding Specificity: AA 260-565

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RYK antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This RYK antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 260-565 amino acids from human RYK.

Clone: 1671CT575-42-61

Isotype: IgG1 kappa

Application Details

Application Notes: WB: 1:1000. FC: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for RYK

Target: RYK (RYK Receptor-Like Tyrosine Kinase (RYK))

Alternative Name: RYK (RYK Products)

Synonyms: RYK antibody, jtk5 antibody, ryk1 antibody, jtk5a antibody, d3s3195 antibody, wu:fb37b12 antibody, wu:fi05b06 antibody, zgc:158381 antibody, MGC114645 antibody, D3S3195 antibody, JTK5 antibody, JTK5A antibody, RYK1 antibody, AW536699 antibody, ERK-3 antibody, Vik antibody, receptor-like tyrosine kinase antibody, receptor-like tyrosine kinase S homeolog antibody, tyrosine-protein kinase RYK antibody, RYK antibody, ryk antibody, ryk.S antibody, LOC100541106 antibody, Ryk antibody

Background: May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C- terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.

Molecular Weight: 67815

UniProt: P34925

Pathways: RTK Signaling, WNT Signaling, Regulation of Cell Size