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RUNX2 antibody (N-Term)

RUNX2 Reactivity: Human IHC (p) Host: Rabbit Polyclonal RB10543 unconjugated
Catalog No. ABIN6243280
  • Target See all RUNX2 Antibodies
    RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
    Binding Specificity
    • 16
    • 16
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term
    Reactivity
    • 115
    • 46
    • 30
    • 10
    • 9
    • 8
    • 8
    • 7
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 105
    • 12
    Rabbit
    Clonality
    • 98
    • 19
    Polyclonal
    Conjugate
    • 59
    • 8
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RUNX2 antibody is un-conjugated
    Application
    • 92
    • 46
    • 31
    • 25
    • 10
    • 9
    • 9
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This RUNX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1~30 amino acids from the N-terminal region of human RUNX2.
    Clone
    RB10543
    Isotype
    Ig Fraction
    Top Product
    Discover our top product RUNX2 Primary Antibody
  • Application Notes
    IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Ushijima, Okazaki, Tsushima, Iwamoto: "CCAAT/enhancer-binding protein β regulates the repression of type II collagen expression during the differentiation from proliferative to hypertrophic chondrocytes." in: The Journal of biological chemistry, Vol. 289, Issue 5, pp. 2852-63, (2014) (PubMed).

  • Target
    RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
    Alternative Name
    RUNX2 (RUNX2 Products)
    Background
    Runx2 is a member of the RUNX family of transcription factors. It is a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. It can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in the Runx2 gene have been associated with the bone development disorder cleidocranial dysplasia (CCD).
    Molecular Weight
    56648
    NCBI Accession
    NP_001015051, NP_001019801
    UniProt
    Q13950
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