LMCD1 antibody (C-Term)

Catalog No. ABIN6243246

Product Details anti-LMCD1 Antibody

Target: LMCD1 (LIM and Cysteine-Rich Domains 1 (LMCD1))

Binding Specificity: AA 316-350, C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LMCD1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This LMCD1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 316-350 amino acids from the C-terminal region of human LMCD1.

Clone: RB40473

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for LMCD1

Target: LMCD1 (LIM and Cysteine-Rich Domains 1 (LMCD1))

Alternative Name: LMCD1 (LMCD1 Products)

Synonyms: LMCD1 antibody, AW455500 antibody, AW553074 antibody, dyxin antibody, LIM and cysteine rich domains 1 antibody, LIM and cysteine-rich domains 1 antibody, LMCD1 antibody, lmcd1 antibody, Lmcd1 antibody

Background: Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue- specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity). Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway.

Molecular Weight: 40833

UniProt: Q9NZU5