GAS6 antibody (AA 242-275)

Catalog No. ABIN6243213

Product Details anti-GAS6 Antibody

Target: GAS6 (Growth Arrest-Specific 6 (GAS6))

Binding Specificity: AA 242-275

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAS6 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GAS6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 242-275 amino acids from the Central region of human GAS6.

Clone: RB55872

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for GAS6

Target: GAS6 (Growth Arrest-Specific 6 (GAS6))

Alternative Name: GAS6 (GAS6 Products)

Synonyms: fj34a12 antibody, zgc:63860 antibody, wu:fj34a12 antibody, MGC68463 antibody, gas6 antibody, MGC83872 antibody, GAS6 antibody, Gas-6 antibody, AXLLG antibody, AXSF antibody, growth arrest specific 6 antibody, growth arrest-specific 6 antibody, growth arrest specific 6 L homeolog antibody, growth arrest specific 6 S homeolog antibody, GAS6 antibody, gas6 antibody, gas6.L antibody, gas6.S antibody, Gas6 antibody

Background: Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.

Molecular Weight: 74925

UniProt: Q14393

Pathways: RTK Signaling, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response