This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This TFDP2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 175-208 amino acids from the Central region of human TFDP2.
Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F1/DP complex appears to mediate both cell proliferation and apoptosis.