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DNMT3B antibody (AA 356-390)

DNMT3B Reactivity: Mouse WB Host: Rabbit Polyclonal RB50993 unconjugated
Catalog No. ABIN6243167
  • Target See all DNMT3B Antibodies
    DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))
    Binding Specificity
    • 18
    • 16
    • 8
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 356-390
    Reactivity
    • 86
    • 52
    • 32
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Mouse
    Host
    • 81
    • 6
    • 2
    • 1
    Rabbit
    Clonality
    • 75
    • 15
    Polyclonal
    Conjugate
    • 35
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This DNMT3B antibody is un-conjugated
    Application
    • 71
    • 36
    • 24
    • 21
    • 13
    • 13
    • 11
    • 8
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This Mouse Dnmt3b antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 356-390 amino acids from the Central region of Mouse Dnmt3b.
    Clone
    RB50993
    Isotype
    Ig Fraction
    Top Product
    Discover our top product DNMT3B Primary Antibody
  • Application Notes
    WB: 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Target
    DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))
    Alternative Name
    Dnmt3b (DNMT3B Products)
    Synonyms
    DNMT3B antibody, LOC100218113 antibody, ICF antibody, ICF1 antibody, M.HsaIIIB antibody, MmuIIIB antibody, cb91 antibody, dnmt3bl antibody, dnmt7 antibody, sb:cb91 antibody, wu:fb16h07 antibody, DNA methyltransferase 3 beta antibody, DNA methyltransferase 3B antibody, DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a antibody, DNMT3B antibody, Dnmt3b antibody, dnmt3b antibody, dnmt3ba antibody
    Background
    Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. May preferentially methylates nucleosomal DNA within the nucleosome core region. May function as transcriptional co- repressor by associating with CBX4 and independently of DNA methylation. Seems to be involved in gene silencing. In association with DNMT1 and via the recruitment of CTCFL/BORIS, involved in activation of BAG1 gene expression by modulating dimethylation of promoter histone H3 at H3K4 and H3K9. Function as transcriptional corepressor by associating with ZHX1 (By similarity).
    Molecular Weight
    97228
    UniProt
    O88509
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