DNMT3A antibody (AA 463-497)
-
- Target See all DNMT3A Antibodies
- DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))
-
Binding Specificity
- AA 463-497
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This DNMT3A antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Predicted Reactivity
- C, M, Rat
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This DNMT3A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 463-497 amino acids from the Central region of human DNMT3A.
- Clone
- RB51574
- Isotype
- Ig Fraction
- Top Product
- Discover our top product DNMT3A Primary Antibody
-
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 457-486) antibody
DNMT3A Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal RB01852 unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 500-700) antibodyDNMT3A Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 26-100) antibodyDNMT3A Reactivity: Human, Mouse, Rat FACS, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 46-180) antibodyDNMT3A Reactivity: Human ELISA, IHC, FACS Host: Mouse Monoclonal 4G5F11 unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (2meLys44) antibodyDNMT3A Reactivity: Human, Mouse, Rat IF Host: Rabbit Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 457-486) antibodyDNMT3A Reactivity: Human, Mouse WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 1-912) antibodyDNMT3A Reactivity: Human WB, IF Host: Mouse Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 680-902) antibodyDNMT3A Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 723-752), (C-Term) antibodyDNMT3A Reactivity: Human WB Host: Rabbit Polyclonal RB12504 unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 31-61), (N-Term) antibodyDNMT3A Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB15267 unconjugated
-
- Application Notes
- WB: 1:1000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Expiry Date
- 6 months
-
- Target
- DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))
- Alternative Name
- DNMT3A (DNMT3A Products)
- Synonyms
- DNMT3A antibody, DNMT3A2 antibody, M.HsaIIIA antibody, MmuIIIA antibody, dnmt3a1 antibody, dnmt6 antibody, DNA methyltransferase 3 alpha antibody, DNA methyltransferase 3A antibody, DNA (cytosine-5-)-methyltransferase 3 alpha b antibody, DNMT3A antibody, Dnmt3a antibody, dnmt3a antibody, dnmt3ab antibody
- Background
- Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZBTB18. Recruited to trimethylated 'Lys-36' of histone H3 (H3K36me3) sites. Can actively repress transcription through the recruitment of HDAC activity.
- Molecular Weight
- 101858
- UniProt
- Q9Y6K1
-
