BIRC6 antibody (AA 4810-4844)

Catalog No. ABIN6243063

Product Details anti-BIRC6 Antibody

Target: BIRC6 (Baculoviral IAP Repeat-Containing 6 (BIRC6))

Binding Specificity: AA 4810-4844

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BIRC6 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This BIRC6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 4810-4844 amino acids from human BIRC6.

Clone: RB56699

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. FC: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for BIRC6

Target: BIRC6 (Baculoviral IAP Repeat-Containing 6 (BIRC6))

Alternative Name: BIRC6 (BIRC6 Products)

Synonyms: APOLLON antibody, BRUCE antibody, bruce antibody, apollon antibody, BIRC6 antibody, A430032G04Rik antibody, A430040A19Rik antibody, AA501170 antibody, Bruce antibody, D630005A10Rik antibody, mKIAA1289 antibody, baculoviral IAP repeat containing 6 antibody, baculoviral IAP repeat-containing 6 antibody, BIRC6 antibody, Birc6 antibody, birc6 antibody

Background: Anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase. Has an unusual ubiquitin conjugation system in that it could combine in a single polypeptide, ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity, forming a chimeric E2/E3 ubiquitin ligase. Its tragets include CASP9 and DIABLO/SMAC. Acts as an inhibitor of CASP3, CASP7 and CASP9. Important regulator for the final stages of cytokinesis. Crucial for normal vesicle targeting to the site of abscission, but also for the integrity of the midbody and the midbody ring, and its striking ubiquitin modification.

Molecular Weight: 530255

UniProt: Q9NR09