APLP1 antibody (AA 505-539)

Catalog No. ABIN6243047

Product Details anti-APLP1 Antibody

Target: APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))

Binding Specificity: AA 505-539

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APLP1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This APLP1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 505-539 amino acids from the human region of human APLP1.

Clone: RB58020

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000. FC: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for APLP1

Target: APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))

Alternative Name: APLP1 (APLP1 Products)

Background: May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity). Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I.

Molecular Weight: 72176

UniProt: P51693

Pathways: cAMP Metabolic Process