ACOT8 antibody (C-Term)

Catalog No. ABIN6242996

Product Details anti-ACOT8 Antibody

Target: ACOT8 (Acyl-CoA Thioesterase 8 (ACOT8))

Binding Specificity: AA 275-310, C-Term

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACOT8 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ACOT8 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 275-310 amino acids from the C-terminal region of human ACOT8.

Clone: RB48192

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for ACOT8

Target: ACOT8 (Acyl-CoA Thioesterase 8 (ACOT8))

Alternative Name: ACOT8 (ACOT8 Products)

Synonyms: PTE1 antibody, zgc:101691 antibody, HNAACTE antibody, PTE-1 antibody, PTE-2 antibody, PTE2 antibody, hACTE-III antibody, hTE antibody, Pte1 antibody, acyl-CoA thioesterase 8 antibody, ACOT8 antibody, acot8 antibody, Acot8 antibody

Background: Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. May mediate Nef-induced down-regulation of CD4. Major thioesterase in peroxisomes. Competes with BAAT (Bile acid CoA: amino acid N- acyltransferase) for bile acid-CoA substrate (such as chenodeoxycholoyl-CoA). Shows a preference for medium-length fatty acyl-CoAs (By similarity). May be involved in the metabolic regulation of peroxisome proliferation.

Molecular Weight: 35914

UniProt: O14734

Pathways: Monocarboxylic Acid Catabolic Process