MGC130979 antibody, SPTLC2L antibody, RGD1310030 antibody, C20orf38 antibody, LCB2B antibody, LCB3 antibody, SPT3 antibody, dJ718P11 antibody, dJ718P11.1 antibody, hLCB2b antibody, C130053K05Rik antibody, serine palmitoyltransferase long chain base subunit 3 antibody, serine palmitoyltransferase, long chain base subunit 3 S homeolog antibody, serine palmitoyltransferase 3 antibody, serine palmitoyltransferase, long chain base subunit 3 antibody, SPTLC3 antibody, sptlc3.S antibody, LOC100438231 antibody, sptlc3 antibody, LOC100546896 antibody, Sptlc3 antibody
Background
Serine palmitoyltransferase (SPT). The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC3-SPTSSA isozyme uses both C14-CoA and C16-CoA as substrates, while the SPTLC1-SPTLC3-SPTSSB has the ability to use a broader range of acyl-CoAs without apparent preference.