NCR3 antibody (AA 31-65)

Catalog No. ABIN6242894

Product Details anti-NCR3 Antibody

Target: NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))

Binding Specificity: AA 31-65

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCR3 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: H

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NCR3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 31-65 amino acids from the human region of human NCR3.

Clone: RB57884

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for NCR3

Target: NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))

Alternative Name: NCR3 (NCR3 Products)

Synonyms: MGC133750 antibody, 1C7 antibody, CD337 antibody, LY117 antibody, MALS antibody, NKp30 antibody, Nkp30 antibody, natural cytotoxicity triggering receptor 3 antibody, NCR3 antibody, Ncr3 antibody

Background: Cytotoxicity-activating receptor that contributes to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation.

Molecular Weight: 21593

UniProt: O14931

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process