STUB1 antibody
-
- Target See all STUB1 Antibodies
- STUB1 (STIP1 Homology and U-Box Containing Protein 1 (STUB1))
-
Reactivity
- Human, Mouse
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- This STUB1 antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Purification
- This antibody is purified through a protein G column, followed by dialysis against PBS.
- Immunogen
- This STUB1 antibody is generated from a mouse immunized with a recombinant protein of human STUB1.
- Clone
- 1008CT12-4-1
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product STUB1 Primary Antibody
-
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 1-303) antibody
STUB1 Reactivity: Human WB, IF, IP Host: Rabbit Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (C-Term) antibodyVerified STUB1 Reactivity: Human WB, ELISA, IHC Host: Goat Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) antibodySTUB1 Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Dog, Pig, Horse, Monkey, Chicken, Hamster, Avian, Cat, Donkey, Goat, Rabbit, Sheep WB Host: Goat Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 203-231) antibodySTUB1 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 203-231), (C-Term) antibodySTUB1 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB7393 unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 1-303) antibodySTUB1 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 1-48) antibodySTUB1 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 236-263), (C-Term) antibodySTUB1 Reactivity: Human WB, FACS Host: Rabbit Polyclonal RB32217 unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 51-303) antibodySTUB1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (N-Term) antibodySTUB1 Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Zebrafish (Danio rerio) WB, IHC Host: Rabbit Polyclonal unconjugated
-
- Application Notes
- WB: 1:4000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Expiry Date
- 6 months
-
- Target
- STUB1 (STIP1 Homology and U-Box Containing Protein 1 (STUB1))
- Alternative Name
- STUB1 (STUB1 Products)
- Background
- E3 ubiquitin-protein ligase which targets misfolded chaperone substrates towards proteasomal degradation. Collaborates with ATXN3 in the degradation of misfolded chaperone substrates: ATXN3 restricting the length of ubiquitin chain attached to STUB1/CHIP substrates and preventing further chain extension. Ubiquitinates NOS1 in concert with Hsp70 and Hsp40. Modulates the activity of several chaperone complexes, including Hsp70, Hsc70 and Hsp90. Mediates transfer of non-canonical short ubiquitin chains to HSPA8 that have no effect on HSPA8 degradation. Mediates polyubiquitination of DNA polymerase beta (POLB) at 'Lys-41', 'Lys-61' and 'Lys-81', thereby playing a role in base-excision repair: catalyzes polyubiquitination by amplifying the HUWE1/ARF- BP1-dependent monoubiquitination and leading to POLB-degradation by the proteasome. Mediates polyubiquitination of CYP3A4. Ubiquitinates EPHA2 and may regulate the receptor stability and activity through proteasomal degradation.
- Molecular Weight
- 34856
- UniProt
- Q9UNE7
- Pathways
- Regulation of Hormone Metabolic Process, Response to Water Deprivation
-
