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KCNMA1 antibody (AA 118-152)
KCNMA1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
RB53642
unconjugated
Product Details anti-KCNMA1 Antibody
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Target
See all KCNMA1 Antibodies
KCNMA1
(Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1))
Binding Specificity
All epitopes for KCNMA1 antibodies
AA 118-152
Reactivity
All reactivities for KCNMA1 antibodies
Human
Host
All hosts for KCNMA1 antibodies
Rabbit
Clonality
All clonalities for KCNMA1 antibodies
Polyclonal
Conjugate
All conjugates for KCNMA1 antibodies
This KCNMA1 antibody is un-conjugated
Application
All applications for KCNMA1 antibodies
Western Blotting (WB)
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This KCNMA1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 118-152 amino acids from human KCNMA1.
Clone
RB53642
Isotype
Ig Fraction
Top Product
Discover our top product KCNMA1 Primary Antibody
Alternatives
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anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (C-Term) antibody
KCNMA1
Reactivity: Human, Rat, Mouse, Zebrafish (Danio rerio), Cow, Rabbit, Dog, Horse, Guinea Pig, Sheep
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (AA 1080-1129) antibody
KCNMA1
Reactivity: Human, Rat, Mouse, Cow, Rabbit, Horse, Guinea Pig, Sheep, Chicken, Xenopus laevis, Monkey, Pig, Bat
WB, IHC, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (AA 1184-1200), (C-Term), (Intracellular) antibody
KCNMA1
Reactivity: Human, Rat, Mouse
WB, IHC, IF, IP, ICC
Host: Rabbit
Polyclonal
unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (AA 641-690) antibody
KCNMA1
Reactivity: Human, Rat, Mouse, Zebrafish (Danio rerio), Cow, Rabbit, Dog, Horse, Guinea Pig, Sheep, Monkey, Pig, Bat
WB
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
WB: 1:500
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Expiry Date
6 months
Target Details for KCNMA1
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Target
KCNMA1
(Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1))
Alternative Name
KCNMA1 (KCNMA1 Products )
Synonyms
BKTM antibody, KCa1.1 antibody, MaxiK antibody, SAKCA antibody, SLO antibody, SLO-ALPHA antibody, SLO1 antibody, bA205K10.1 antibody, mSLO1 antibody, DDBDRAFT_0190653 antibody, DDBDRAFT_0235401 antibody, DDB_0190653 antibody, DDB_0235401 antibody, KCNMA antibody, KCNMA1 antibody, 5730414M22Rik antibody, BKCa antibody, Slo antibody, Slo1 antibody, mSlo antibody, mSlo1 antibody, KCNMA1b antibody, KCNMA1c antibody, Kcnma antibody, bktm antibody, kcnma1-A antibody, sakca antibody, cSlo antibody, slo1 antibody, kcnma1 antibody, si:ch211-39f22.2 antibody, BcDNA:GH10751 antibody, CG10693 antibody, Dmel\CG10693 antibody, Dslo antibody, dSlo antibody, dSlo1 antibody, dslo antibody, fSlo antibody, potassium calcium-activated channel subfamily M alpha 1 antibody, calcium-activated BK potassium channel, alpha subunit antibody, potassium large conductance calcium-activated channel, subfamily M, alpha member 1 antibody, potassium calcium-activated channel subfamily M alpha 1 L homeolog antibody, potassium large conductance calcium-activated channel, subfamily M, alpha member 1a antibody, calcium-activated potassium channel subunit alpha-1 antibody, slowpoke antibody, KCNMA1 antibody, kcnma1 antibody, Kcnma1 antibody, kcnma1.L antibody, kcnma1a antibody, LOC100454095 antibody, slo antibody
Background
Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in the cochlea, regulation of transmitter release, and innate immunity. In smooth muscles, its activation by high level of Ca(2+), caused by ryanodine receptors in the sarcoplasmic reticulum, regulates the membrane potential. In cochlea cells, its number and kinetic properties partly determine the characteristic frequency of each hair cell and thereby helps to establish a tonotopic map. Kinetics of KCNMA1 channels are determined by alternative splicing, phosphorylation status and its combination with modulating beta subunits. Highly sensitive to both iberiotoxin (IbTx) and charybdotoxin (CTX).
Molecular Weight
137560
UniProt
Q12791
Pathways
Regulation of Hormone Metabolic Process , Sensory Perception of Sound
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