HOPX antibody (AA 22-54)

Catalog No. ABIN6242849

Product Details anti-HOPX Antibody

Target: HOPX (HOP Homeobox (HOPX))

Binding Specificity: AA 22-54

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOPX antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Hopx antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 22-54 amino acids from the Central region of Mouse Hopx.

Clone: RB51159

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for HOPX

Target: HOPX (HOP Homeobox (HOPX))

Alternative Name: Hopx (HOPX Products)

Synonyms: CAMEO antibody, HOD antibody, HOP antibody, LAGY antibody, NECC1 antibody, OB1 antibody, SMAP31 antibody, TOTO antibody, 1110018K11Rik antibody, 1200015P04Rik antibody, 2300002F06Rik antibody, AI848177 antibody, AW490897 antibody, Cameo antibody, Hdop antibody, Hod antibody, Hop antibody, Ob1 antibody, Obl antibody, Toto antibody, GIIg15b antibody, HOPX antibody, hod antibody, hop antibody, ob1 antibody, lagy antibody, toto antibody, cameo antibody, necc1 antibody, smap31 antibody, MGC147344 antibody, HOP homeobox antibody, HOPX antibody, Hopx antibody, hopx antibody

Background: Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy.

Molecular Weight: 8282

UniProt: Q8R1H0

Pathways: Regulation of Muscle Cell Differentiation