This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This CLEC16A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 773-805 amino acids from the C-terminal region of human CLEC16A.
CLEC16A antibody, Gop-1 antibody, KIAA0350 antibody, 4932416N17Rik antibody, curt antibody, mKIAA0350 antibody, RGD1305773 antibody, C-type lectin domain family 16 member A antibody, C-type lectin domain containing 16A antibody, C-type lectin domain family 16, member A antibody, CLEC16A antibody, clec16a antibody, Clec16a antibody
Background
Regulator of mitophagy through the upstream regulation of the RNF41/NRDP1-PARK2 pathway. Mitophagy is a selective form of autophagy necessary for mitochondrial quality control. The RNF41/NRDP1-PARK2 pathway regulates autophagosome-lysosome fusion during late mitophagy. May protect RNF41/NRDP1 from proteosomal degradation, RNF41/NRDP1 which regulates proteosomal degradation of PARK2. Plays a key role in beta cells functions by regulating mitophagy/autophagy and mitochondrial health.