Sonic Hedgehog antibody (C-Term)
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- Target See all Sonic Hedgehog (SHH) Antibodies
- Sonic Hedgehog (SHH)
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Binding Specificity
- AA 397-431, C-Term
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Reactivity
- Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Sonic Hedgehog antibody is un-conjugated
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Application
- Western Blotting (WB), Flow Cytometry (FACS)
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This Mouse Shh antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 397-431 amino acids from the C-terminal region of mouse Shh.
- Clone
- RB51214
- Isotype
- Ig Fraction
- Top Product
- Discover our top product SHH Primary Antibody
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anti-Sonic Hedgehog (SHH) (AA 21-120) antibody
SHH Reactivity: Human, Mouse, Rat, Pig WB, ELISA, IF (cc), IHC (p), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Sonic Hedgehog (SHH) (AA 26-161) antibodySHH Reactivity: Human WB, IHC, ELISA, FACS Host: Mouse Monoclonal 5H4 unconjugated
anti-Sonic Hedgehog (SHH) (C-Term) antibodyVerified SHH Reactivity: Human, Mouse WB, ELISA, IF, FACS Host: Goat Polyclonal unconjugated
anti-Sonic Hedgehog (SHH) (N-Term) antibodySHH Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Dog, Cow, Guinea Pig, Horse, Goat, Rabbit WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Sonic Hedgehog (SHH) (AA 36-193) antibodySHH Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Sonic Hedgehog (SHH) (AA 36-193) antibodySHH Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal D6 unconjugated
anti-Sonic Hedgehog (SHH) (AA 58-91), (N-Term) antibodySHH Reactivity: Human, Mouse, Rat WB, IF, IHC (p), FACS Host: Rabbit Polyclonal RB52387 unconjugated
anti-Sonic Hedgehog (SHH) (AA 24-197) antibodySHH Reactivity: Human, Rat, Dog, Monkey WB, IF Host: Mouse Monoclonal 10H6 unconjugated
anti-Sonic Hedgehog (SHH) (AA 237-399) antibodySHH Reactivity: Rat WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-Sonic Hedgehog (SHH) (AA 203-218), (N-Term) antibodySHH Reactivity: Human, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB: 1:1000. FC: 1:25
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Expiry Date
- 6 months
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- Target
- Sonic Hedgehog (SHH)
- Alternative Name
- Shh (SHH Products)
- Background
- Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO. Also regulates another target, the gli oncogene. Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction (By similarity).
- Molecular Weight
- 47773
- UniProt
- Q62226
- Pathways
- Hedgehog Signaling, Dopaminergic Neurogenesis, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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